Pittsburgh - Rochester New York  (1:0)

US Open Cup

05.04

Hartford Athletic - Lansdowne Bhoys  (3:0)

US Open Cup

04.04

Miami - Jacksonville A. U23  (3:1)

US Open Cup

04.04

Tampa Bay Rowdies - Nona  (2:0)

US Open Cup

04.04

One Knoxville SC - Memphis 901  (1:1)

US Open Cup

04.04

Flower City Union - Manhattan SC  (3:1)

US Open Cup

04.04

New Mexico - Uda Soccer  (6:0)

US Open Cup

04.04

Oakland Roots SC - El Farolito  (3:1)

US Open Cup

04.04

Charlotte Independ. - Appalachian  (2:0)

US Open Cup

05.04

Louisville City - Lexington SC  (1:0)

US Open Cup

05.04

Chattanooga - Birmingham Legion  (1:4)

US Open Cup

05.04

Tormenta - Rio Grande  (2:1)

US Open Cup

05.04

Loudoun United - North Carolina  (1:1)

US Open Cup

05.04

Maryland Bobcats - Nor'easters  (2:2)

US Open Cup

05.04

Union Omaha SC - El Paso Locomotive  (2:0)

US Open Cup

05.04

Tulsa Athletics - Tulsa  (1:0)

US Open Cup

05.04

Des Moines Menace - Chattanooga  (1:4)

US Open Cup

05.04

Indy Eleven - Michigan Stars  (1:1)

US Open Cup

05.04

Colorado Springs - Northern Colorado  (1:1)

US Open Cup

05.04

Diego Loyal - ASC San Diego  (2:0)

US Open Cup

05.04

Orange County SC - Capo  (5:0)

US Open Cup

05.04

Las Vegas Lights - Los Angeles Force  (4:0)

US Open Cup

05.04

Phoenix Rising - Greenville Triumph SC  (1:0)

US Open Cup

05.04

Sacramento Republic - Crossfire Redmond  (2:2)

US Open Cup

05.04

Central Valley Fuego - Monterey Bay  (0:0)

US Open Cup

05.04

Detroit City - Gold Star Detroit  (1:0)

US Open Cup

04.04

Charleston Battery - Savannah Clovers  (4:1)

US Open Cup

05.04

San Antonio - Orlando Lyon  (1:1)

US Open Cup

05.04